Gene information
Official symbol CACNA1H
Official full name calcium voltage-gated channel subunit alpha1 H
Gene type protein-coding gene
Chromosome16p13.3
Alias symbolCav3.2
Gene familyCalcium voltage-gated channel alpha1 subunits
Resources
Entrez Gene 8912
HGNC HGNC:1395
Ensembl ENSG00000196557
Vega OTTHUMG00000172992
UCSC uc002cks.4
GO terms: 36 records
GO Description Category LogP Number of genes Detail
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0005216 ion channel activity GO Molecular Functions -2.12987867 14 More
GO:0005244 voltage-gated ion channel activity GO Molecular Functions -1.48636532 7 More
GO:0005261 cation channel activity GO Molecular Functions -1.68739377 23 More
GO:0006816 calcium ion transport GO Biological Processes -5.55009887 27 More
GO:0007517 muscle organ development GO Biological Processes -15.8908392 49 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0010038 response to metal ion GO Biological Processes -20.5090881 61 More
GO:0015267 channel activity GO Molecular Functions -2.12225487 15 More
GO:0015318 inorganic molecular entity transmembrane transporter activity GO Molecular Functions -2.11605072 20 More
GO:0022803 passive transmembrane transporter activity GO Molecular Functions -2.11455525 15 More
GO:0022832 voltage-gated channel activity GO Molecular Functions -1.48636532 7 More
GO:0022836 gated channel activity GO Molecular Functions -2.68852033 13 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0042692 muscle cell differentiation GO Biological Processes -15.1559811 45 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051146 striated muscle cell differentiation GO Biological Processes -10.9431474 33 More
GO:0061061 muscle structure development GO Biological Processes -23.2569142 77 More
GO:0070588 calcium ion transmembrane transport GO Biological Processes -2.54626507 17 More
GO:0071241 cellular response to inorganic substance GO Biological Processes -4.23170629 23 More
GO:0071248 cellular response to metal ion GO Biological Processes -4.26641514 21 More
GO:1903307 positive regulation of regulated secretory pathway GO Biological Processes -2.97443173 8 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1990351 transporter complex GO Cellular Components -2.10211936 13 More
GO:2000241 regulation of reproductive process GO Biological Processes -4.23306387 21 More
GO:2000243 positive regulation of reproductive process GO Biological Processes -2.52693001 10 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04020 Calcium signaling pathway KEGG Pathway -10.4415222 36 More
Drug-Gene interaction
view
Related drugs: 27 records
Drug name Interaction type Source PMID View
abt-639 blocker TTD view
atagabalin modulator ChemblInteractions view
bepridil hydrochloride blocker ChemblInteractions view
celecoxib PharmGKB 22336956 view
chembl1570199 DTC view
chembl374632 DTC view
chembl526952 DTC view
chembl533602 DTC view
chembl592106 DTC view
chembl592566 DTC view
elliptecine DTC view
ethosuximide blocker ChemblInteractions view
flunarizine inhibitor TdgClinicalTrialTENDTTD 1958259311784784117523521713928417016423 view
flunarizine dihydrochloride DTC view
gabapentin modulator ChemblInteractions view
gabapentin enacarbil modulator ChemblInteractions view
imagabalin modulator ChemblInteractions view
methsuximide blocker ChemblInteractions view
mibefradil blockerinhibitor TTD 1719090314993472967092394816121549881893759391689999015562257 view
mibefradil dihydrochloride blocker ChemblInteractions view
naftopidil DTC view
oxatomide DTC view
paramethadione blocker ChemblInteractions view
phensuximide blocker ChemblInteractions view
pregabalin modulator ChemblInteractions view
trimethadione blocker ChemblInteractions view
zonisamide inhibitor TdgClinicalTrial 19557119200014331776232019948168155116911496533120025128205027221470446318433351 view
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
Chr16:1080385 hypermethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
Chr16:1181443 hypermethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
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